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You are here:Home » Antibodies » Abs to Enzymes, Decarboxylase » Anti -GLDC, NT (GLDC, GCSP, Glycine dehydrogenase [decarboxylating], mitochondrial, Glycine cleavage system P protein, Glycine decarboxylase)

Anti -GLDC, NT (GLDC, GCSP, Glycine dehydrogenase [decarboxylating], mitochondrial,
Glycine cleavage system P protein, Glycine decarboxylase)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
Catalog #036074
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenGLDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56~85 amino acids from the N-terminal region of human GLDC.
SpecificityHuman, mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesGLDC, GCSP, Glycine dehydrogenase [decarboxylating], mitochondrial, Glycine cleavage system P protein, Glycine decarboxylase


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