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You are here:Home » Antibodies » Abs to Ribosomal Proteins » Anti -LAS1L (FLJ12525, FLJ30133, FLJ45274, dJ475B7.2, Protein LAS1 homolog)

Anti -LAS1L (FLJ12525, FLJ30133, FLJ45274, dJ475B7.2, Protein LAS1 homolog)


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Clone Host Grade Applications
Monoclonal Rabbit Supernatant B FC
LAS1L is a nuclear protein essential for cell proliferation and ribosome synthesis; particularly the biogenesis of the 60S ribosomal subunits (1, 2). It is also required for maturation of the 28S rRNA (1). Depletion of LAS1L has shown to cause nucleolar disorganization and inhibit cell proliferation characterized by a p53-dependent G1 cell by cycle arrest (2).
Catalog #045518
ApplicationsSuitable for use in Flow Cytometry and Western Blot. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:10-100
Western Blot: 1:1000-10,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone No13C75
ConcentrationNot determined
FormSupplied as a liquid in PBS, sodium azide, BSA, glycerol.
ImmunogenSynthetic peptide corresponding to residues in human LAS1L.
SpecificityRecognizes human LAS1L.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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