Applications
This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] Suitable for use in Immunohistochemistry. Other applications not tested.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Specificity
Recognizes human CADM2. Species sequence homology: Gorilla, gibbon, monkey, marmoset, bovine, canine, bat, elephant, panda, equine, rabbit, porcine, opossum (100%), mouse, rat, hamster (94%), platypus (88%), turkey, chicken, xenopus, pufferfish, stickleback (81%).