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You are here:Home » Antibodies » Antibodies-Coagulation Factors » Anti -Beta-Thromboglobulin (bTG)

Anti -Beta-Thromboglobulin (bTG)


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH IC
Beta-thromboglobulin ( -thromboglobulin, also called Pro-Platelet basic protein or BTG) is a protein that is stored in alpha-granules of platelets and released in large amounts after platelet activation.[1] It is a type of Chemokine (C-X-C motif) ligand 7.[2]  Beta-Thromboglobulin is a chemoattractant, strongly for fibroblasts and weakly for neutrophils. It is a stimulator of mitogenesis, extracellular matrix synthesis, glucose metabolism, and plasminogen activator synthesis in human fibroblasts.[1] Beta-Thromboglobulin also affects megakaryocyte maturation, and thus helps in regulating platelet production.[1] Levels of Beta-Thromboglobulin is used to index platelet activation. It is measured by ELISA in blood plasma or urine, and often in conjunction with Platelet factor 4)[1] It is elevated in diabetes mellitus.[3]
Catalog #139412
ApplicationsSuitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested.
Recommended DilutionELISA: 1:100-200
Western Blot: 1:100-400
Immunocytochemistry: 1:100-500 (formalin fixed cells)
Immunohistochemistry: 1:100-500 (formalin fixed frozen sections)
Immunohistochemistry: 1:50-200 (paraffin sections)
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No13j16
FormSupplied as a liquid in PBS, pH 7.2, 0.05% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
SpecificityRecognizes human Beta-Thromboglobulin (bTG)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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