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You are here:Home » Antibodies » Antibodies-Coagulation Factors » Anti -Antiplasmin, Alpha 2

Anti -Antiplasmin, Alpha 2


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Apha-2 antiplasmin is a single-chain glycoprotein with a molecular weight of about 65000. The
normal concentration in human plasma is 60mg/ml. Platelets contain significant amounts of the
protein, which is released along with platelet factor 4, following thrombin stimulation. It can form
1:1 complexes with circulating plasmin. Alpha-2 antiplasmin is the most important inhibitor of
plasmin-mediated fibrinolysis, but also capable of inactivating factor XIIa, kallikrein, factor XIa,
thrombin and factor Xa. The importance of the alpha-2 antiplasmin as regulator of the fibrinolytic
system was detected by the discovery of a congenital deficiency.
Catalog #171464
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:50,000
Western Blot: 1-5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No14D10
FormSupplied as a liquid in 0.05M Sodium Phosphate, pH 6.6, 1mM EDTA, 0.1M sodium chloride.
PurityPurified by Protein A affinity chromatography.
ImmunogenHuman Alpha 2 Antiplasmin.
SpecificityRecognizes human Alpha 2 Antiplasmin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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