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Anti -ABC A7 (ATP-binding Cassette (ABC) Sub-family A Member 7, Macrophage ABC Transporter, Autoantigen SS-N, ABCA-SSN)
Anti -ABC A7 (ATP-binding Cassette (ABC) Sub-family A Member 7, Macrophage ABC
Transporter, Autoantigen SS-N, ABCA-SSN)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
B FC |
|
| ABCA7, an ATP-binding cassette, sub-family A (ABC1), member 7, is highly homologous to ABCA1 and mediates cellular cholesterol and phospholipid release by apolipoproteins. The ABCA7 gene is regulated by sterol in the opposite direction to ABCA1 through SRE/SREBP2. The expression of ABCA7 by this regulation is associated with phagocytic activity. As well, it binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells and may mediate cholesterol efflux. | | | Catalog # | A0004-02P | | Applications | Suitable for use in Flow Cytometry and Western Blot. Not recommended for use in ELISA. Other applications not tested. | | Recommended Dilutions | Flow Cytometry: 1:500-1:4000 | | Western Blot: 1:2000 detects a band at ~240kD. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | Clone Type | Monoclonal | | Isotype | IgG2a,k | | Clone No | 8J150 | | Host | Rat | | Source | Mouse | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in Tris-glycine, 150mM sodium chloride, 0.05% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Mouse ABCA7 stably-transfected HeLa cells. Epitope | | Specificity | Recognizes mouse ABCA7. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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