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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -ABC A7 (ATP-binding Cassette (ABC) Sub-family A Member 7, Macrophage ABC Transporter, Autoantigen SS-N, ABCA-SSN)

Anti -ABC A7 (ATP-binding Cassette (ABC) Sub-family A Member 7, Macrophage ABC
Transporter, Autoantigen SS-N, ABCA-SSN)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified B FC
ABCA7, an ATP-binding cassette, sub-family A (ABC1), member 7, is highly homologous to ABCA1 and mediates cellular cholesterol and phospholipid release by apolipoproteins. The ABCA7 gene is regulated by sterol in the opposite direction to ABCA1 through SRE/SREBP2. The expression of ABCA7 by this regulation is associated with phagocytic activity. As well, it binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells and may mediate cholesterol efflux.
Catalog #A0004-02P
ApplicationsSuitable for use in Flow Cytometry and Western Blot. Not recommended for use in ELISA. Other applications not tested.
Recommended DilutionsFlow Cytometry: 1:500-1:4000
Western Blot: 1:2000 detects a band at ~240kD.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No8J150
HostRat
SourceMouse
Concentration~1mg/ml
FormSupplied as a liquid in Tris-glycine, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenMouse ABCA7 stably-transfected HeLa cells. Epitope
SpecificityRecognizes mouse ABCA7.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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