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Anti -ADAMTS10 (a Metallopeptidase with thrombospondin type 1 motif, 10)
Anti -ADAMTS10 (a Metallopeptidase with thrombospondin type 1 motif, 10)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B IP |
|
| ADAMTS10 belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent metalloproteases. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. Mutations in the ADAMTS10 gene may cause autosomal recessive Weill-Marchesani syndrome. The amino acid sequence of human ADAMTS10 is 100%, 96% and 94% identical to that of chimpanzee, dog and mouse. | | | Catalog # | A0859-63 | | Applications | Suitable for use in ELISA, Western Blot, and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | ELISA: 0.5-1.0ug/ml | | Western Blot: 1-2ug/ml | | Immunoprecipitation: 25ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 9H44 | | Host | Mouse | | Source | Human | | Concentration | ~500ug/ml | | Form | Supplied as a lyophilized powder in 0.2um sterile-filtered solution of 5% trehalose in PBS. Reconstitute with 40-50% glycerol, PBS. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | CHO-derived, recombinant human ADAMTS10 aa1-1103. | | Specificity | Recognizes human ADAMTS10. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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