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ALAS2, Recombinant, Human (Aminolevulinate delta-Synthase 2, Delta ALA Synthetase)
ALAS2, Recombinant, Human (Aminolevulinate delta-Synthase 2, Delta ALA Synthetase)
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| ALAS2 specifies an erythroid-specific mitochondrially located enzyme. It catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified. | | | Catalog # | A1210-03 | | Source | Recombinant human ALAS, aa136-553, with N-terminal His tag, expressed in E. coli. | | Molecular Weight | 46kD | | Applications | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months. | | Molecular Weight | 46kD | | Source | E. coli | | Purity | 90% | | Concentration | As reported | | Form | Supplied as a liquid in 25mM Tris-HCl, pH 8.0, 100mM NaCl, 0.05% Tween-20, 20% glycerol, 3mM DTT, 20uM pyridoxal 5' phosphate monohydrate. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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