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Anguinomycin A (5-Demethyl-leptomycin A, KR 2827A, Antibiotic KR 2827A)
Anguinomycin A (5-Demethyl-leptomycin A, KR 2827A, Antibiotic KR 2827A)
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| Anguinomycin A, isolated from a Streptomyces sp., displays nanomolar cytotoxicity to murine P388 leukemia cells. In addition, it shows antitumour activity in mice against murine Lewis lung carcinoma and P388 leukemia. Anguinomycin A is an analogue of Leptomycin B, an inhibitor of nuclear export of proteins. | | | Catalog # | A2295-11L1 | | Purity | >95% by HPLC | | Solubility | Soluble in ethanol or methanol. Ethanol recommended. Unstable in DMSO. | | Related to | Leptomycin A, Leptomycin B, Kazusamycin A, Kazusamycin B | | CAS Number | 111278-01-4 | | Molecular Formula | C31H44O6 | | Molecular Weight | 512.68 | | Source | Streptomyces sp. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | 5-Demethyl-leptomycin A, KR 2827A, Antibiotic KR 2827A |
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