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You are here:Home » Biochemicals » Biochem-Antibiotics » Anguinomycin A (5-Demethyl-leptomycin A, KR 2827A, Antibiotic KR 2827A)

Anguinomycin A (5-Demethyl-leptomycin A, KR 2827A, Antibiotic KR 2827A)


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Anguinomycin A, isolated from a Streptomyces sp., displays nanomolar cytotoxicity to murine P388 leukemia cells. In addition, it shows antitumour activity in mice against murine Lewis lung carcinoma and P388 leukemia. Anguinomycin A is an analogue of Leptomycin B, an inhibitor of nuclear export of proteins.
Catalog #A2295-11L1
Purity >95% by HPLC
Solubility Soluble in ethanol or methanol. Ethanol recommended. Unstable in DMSO.
Related to Leptomycin A, Leptomycin B, Kazusamycin A, Kazusamycin B
CAS Number111278-01-4
Molecular FormulaC31H44O6
Molecular Weight512.68
SourceStreptomyces sp.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names5-Demethyl-leptomycin A, KR 2827A, Antibiotic KR 2827A

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