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You are here:Home » Antibodies » Abs to G Proteins » Anti -ARHGAP20 (Rho GTPase-activating Protein 20, Rho-type GTPase-activating Protein 20, KIAA1391)

Anti -ARHGAP20 (Rho GTPase-activating Protein 20, Rho-type GTPase-activating Protein 20,
KIAA1391)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
RhoGap20 encodes a potent Rho GTPase-activating protein, which is a direct downstream target of Rap1 in the neurite outgrowth. Overexpression of the protein induced inactivation of Rho for promoting the neurite outgrowth in a Rap1-dependent manner. It is also involved in rearrangements of the cytoskeleton and cell signaling events that occur during spermatogenesis. RhoGap20 gene is predicted to be a tumor suppressor, inactivated by deletion in breast cancer and also by chromosomal translocation in B-cell chronic lymphocytic leukemia. The protein is expressed in human brain, liver, ovary and spinal cord. The gene encoding for rat RhoGap20 is localized on chromosome 8q24.
Catalog #A3570-66L3
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceRat
ConcentrationNot determined.
FormSupplied as a liquid, 0.025% sodium azide, 50% glycerol.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa749-762 ([BLAST]HEGNQETPFTKSKP[BLAST]) of rat RhoGap20.
SpecificityRecognizes rat RhoGap20. Species sequence homology: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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