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You are here:Home » Antibodies » Abs to Drugs » Anti -Benzoylecgonine-Linker (Cocaine)

Anti -Benzoylecgonine-Linker (Cocaine)

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Specifications

Clone Host Grade Applications
Polyclonal Sheep Purified E
Cocaine is a potent psychoactive substance, also known as 'coke' and 'snow' and it is extracted from the leaves of the South American shrub Erythroxylon coca (5, 6). Cocaine hydrochloride is a fine powder that may be insufflated (snorted), producing quick absorption and onset of effects. Intravenous use leads to a quick and powerful but brief effect. 'Crack' is a freebase form of cocaine which when smoked produces an immediate 'high', with a more intense euphoria and so has become the choice for many users (2, 5, 7). Cocaine causes severe psychological dependence. In the body, cocaine is rapidly converted to metabolites by enzymatic and chemical processes. The two major urinary metabolites of cocaine are benzoylecgonine (BZG) and ecgonine methyl ester (8). The plasma half-life of cocaine is only 0.7-1.5 hours and its urinary excretion is rapid. There is very little of the parent cocaine molecule excreted in urine (~1-9%). Benzoylecgonine is the primary urinary metabolite, accounting for 30-40% of the dose eliminated in the urine (2, 6, 9).
Catalog #B1077-14B
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostSheep
Concentration~1mg/ml
FormSupplied as a liquid in 20mM phosphate, 150mM sodium chloride, pH 7.2, 0.09% sodium azide.
PurityPurified
ImmunogenBenzoylecgonine (COOH)-linker (BSA)
SpecificityRecognizes Benzoylecgonine-Linker.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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