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You are here:Home » Biochemicals » Biochem-Antibiotics » Borrelidin (Treponemycin, Antibiotic U 78548, Antibiotic C2989)

Borrelidin (Treponemycin, Antibiotic U 78548, Antibiotic C2989)


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Borrelidin is an unusual nitrile containing metabolite isolated from Streptomyces. Originally discovered as active against against Borrelia species, borrelidin has since found a role as a selective inhibitor of bacterial and eukaryal threonyl-tRNA synthetase. More recent research has found that borrelidin is a very potent angiogenesis inhibitor and induces apoptosis of the capillary tube-forming cells. Borrelidin is an important lead for antimalarial discovery displaying activity against drug-resistant Plasmodia.
Catalog #B2570-28
Purity >99% by HPLC
Solubility Soluble in ethyl acetate, ethanol, methanol, DMF or DMSO.
CAS Number7184-60-3
Molecular FormulaC28H43NO6
Molecular Weight489.64
SourceStreptomyces sp
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesTreponemycin, Antibiotic U 78548, Antibiotic C2989

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