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Borrelidin (Treponemycin, Antibiotic U 78548, Antibiotic C2989)
Borrelidin (Treponemycin, Antibiotic U 78548, Antibiotic C2989)
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| Borrelidin is an unusual nitrile containing metabolite isolated from Streptomyces. Originally discovered as active against against Borrelia species, borrelidin has since found a role as a selective inhibitor of bacterial and eukaryal threonyl-tRNA synthetase. More recent research has found that borrelidin is a very potent angiogenesis inhibitor and induces apoptosis of the capillary tube-forming cells. Borrelidin is an important lead for antimalarial discovery displaying activity against drug-resistant Plasmodia. | | | Catalog # | B2570-28 | | Purity | >99% by HPLC | | Solubility | Soluble in ethyl acetate, ethanol, methanol, DMF or DMSO. | | CAS Number | 7184-60-3 | | Molecular Formula | C28H43NO6 | | Molecular Weight | 489.64 | | Source | Streptomyces sp | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Treponemycin, Antibiotic U 78548, Antibiotic C2989 |
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