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You are here:Home » Antibodies » Abs to Nucleotides » Anti -cAMP (Cyclic Adenosine Monophosphate, Cyclic AMP)

Anti -cAMP (Cyclic Adenosine Monophosphate, Cyclic AMP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum IH
Cyclic adenosine monophosphate or cAMP is an intracellular by-product of ATP by adenylene cyclase when G-protein Coupled Receptors (GPCR) bind various ligands on the cell surface. Cyclic AMP acts as a second messenger for signal transduction across the cell membrane and is a part of kinase activation. It regulates the effects of glucagon and adrenaline along with the movement of calcium ions through ion channels. Since it is affected directly by GPCR activation, cAMP is studied as a means to monitor GPCR in the discovery of therapeutic drugs.
Catalog #B2671-01G
Applications
Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Paraffin): 1:100
Optimal dilutions to be determined by the researcher.
Positive ControlRat hippocampus and cerebellum tissue
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceRat
ConcentrationNot determined.
FormSupplied as a liquid in PBS. Preservative free.
PuritySerum
Immunogen2'O-succinyl cyclic AMP conjugated to BSA.
SpecificityRecognizes rat cAMP.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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