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You are here:Home » Antibodies » Abs to Carbohydrates, Glycoproteins » Anti -Brevican (BEHAB, Brain-Enriched Hyaluronan-Binding Protein)

Anti -Brevican (BEHAB, Brain-Enriched Hyaluronan-Binding Protein)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IC
Brain-enriched hyaluronan-binding protein (Brevican) is a 160kD member of the aggregan/versican proteoglycan family of matrix proteins. It is brain-derived and serves as a linker between HA and other matrix molecules such as tenascins and fibulins. Mature human Brevican contains an N-terminal V-type Ig-like domain (aa52-139), a C-terminal EGF-like (aa646-682) and C-type lectin domain (aa695-802). Multiple isoforms exist where there is an alternate start site at Met228 and a 23aa substitution for aa 649-911 that serves as a GPI-anchor motif. over aa 23-911, human Brevican shares 82% aa identity with mouse Brevican.
Catalog #B2739-70C
ApplicationsSuitable for use in ELISA and Immunocytochemistry. Other applications not tested.
Recommended DilutionImmunocytochemistry: 10ug/ml
Optimal dilutions to be determined by the researcher.
HybridomaMouse myeloma cells with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant human Brevican (aa23-911).
Storage and StabilityLyophilized powder may be stored at -20°C for short-term only. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9L803
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with sterile PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenNS0-derived, recombinant human Brevican (aa23-911; Accession # Q96GW7).
SpecificityRecognizes human Brevican. Species sequence homology: mouse (82%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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