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Anti -Brevican (BEHAB, Brain-Enriched Hyaluronan-Binding Protein)
Anti -Brevican (BEHAB, Brain-Enriched Hyaluronan-Binding Protein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E IC |
|
| Brain-enriched hyaluronan-binding protein (Brevican) is a 160kD member of the aggregan/versican proteoglycan family of matrix proteins. It is brain-derived and serves as a linker between HA and other matrix molecules such as tenascins and fibulins. Mature human Brevican contains an N-terminal V-type Ig-like domain (aa52-139), a C-terminal EGF-like (aa646-682) and C-type lectin domain (aa695-802). Multiple isoforms exist where there is an alternate start site at Met228 and a 23aa substitution for aa 649-911 that serves as a GPI-anchor motif. over aa 23-911, human Brevican shares 82% aa identity with mouse Brevican. | | | Catalog # | B2739-70C | | Applications | Suitable for use in ELISA and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Immunocytochemistry: 10ug/ml | | Optimal dilutions to be determined by the researcher. | | Hybridoma | Mouse myeloma cells with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant human Brevican (aa23-911). | | Storage and Stability | Lyophilized powder may be stored at -20°C for short-term only. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 9L803 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with sterile PBS. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | NS0-derived, recombinant human Brevican (aa23-911; Accession # Q96GW7). | | Specificity | Recognizes human Brevican. Species sequence homology: mouse (82%). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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