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You are here:Home » Antibodies » Abs to Proteins » Anti -BRD3 (Bromodomain-containing Protein 3, RING3-like Protein, KIAA0043, RING3L)

Anti -BRD3 (Bromodomain-containing Protein 3, RING3-like Protein, KIAA0043, RING3L)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
The bromodomain is a conserved 110aa motif which specifically interacts with acetyl-lysines, at least in the context of short histone H3 and H4 peptides. Although bromodomains have now been found in more than 40 different proteins, the function of this motif is poorly understood. The association of two N-terminal bromodomains with a C-terminal extraterminal (ET) domain defines the Fsh/Brd subgroup, which includes members in many species. In vertebrates, four members of the Fsh/Brd subgroup have now been identified: Brd2/RING3/fsrg1, Brd3/ORFX/fsrg2, Brd4/HUNK1/MCAP, and Brd5/BRDT. The Brd3/ORFX gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.
Catalog #B2852-80E
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:32000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to STATTVAPAGIPAT, from N-terminus of the protein sequence according to NP_031397.
SpecificityRecognizes human BRD3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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