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You are here:Home » Antibodies » Abs to CD Markers » Anti -BTLA (B and T lymphocyte associated, BTLA1, CD272, FLJ16065, MGC129743, B and T lymphocyte attenuator) (PE)

Anti -BTLA (B and T lymphocyte associated, BTLA1, CD272, FLJ16065, MGC129743, B and T
lymphocyte attenuator) (PE)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified FC
BTLA, is a 70kD type I membrane glycoprotein that belongs to the CD28 family of receptors. CD28 receptors are Ig superfamily proteins, with an extracellular IgV-like domain, that function as co-stimulatory or co-inhibitory T cell signaling molecules. BTLA is expressed on B cells, T cells, and dendritic cells. Binding of BTLA to its ligand, Herpes virus entry mediator (HVEM, TNFRSF14) triggers a potent inhibitory signal that blocks T cell activation. The aa sequence of the extracellular domain of BTLA shares only 34% identity with that of mouse BTLA. A human BTLA variant lacking the transmembrane domain has been reported.
Catalog #B5001-61C
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Absorption 488nm
Emission 565-605nm
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceMouse
ConcentrationAs reported
FormSupplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant human B and T Lymphocyte Attenuator (rhBTLA; aa5-150 with V105M, S138G, and M148V substitutions) expressed in NSO cells (Q7Z6A9).
SpecificityRecognizes mouse BTLA.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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