You are here:Home
»
Antibodies
»
Abs to CD Markers
»
Anti -BTLA (B and T lymphocyte associated, BTLA1, CD272, FLJ16065, MGC129743, B and T lymphocyte attenuator) (PE)
Anti -BTLA (B and T lymphocyte associated, BTLA1, CD272, FLJ16065, MGC129743, B and T
lymphocyte attenuator) (PE)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
FC |
|
| BTLA, is a 70kD type I membrane glycoprotein that belongs to the CD28 family of receptors. CD28 receptors are Ig superfamily proteins, with an extracellular IgV-like domain, that function as co-stimulatory or co-inhibitory T cell signaling molecules. BTLA is expressed on B cells, T cells, and dendritic cells. Binding of BTLA to its ligand, herpesvirus entry mediator (HVEM, TNFRSF14) triggers a potent inhibitory signal that blocks T cell activation. The aa sequence of the extracellular domain of BTLA shares only 34% identity with that of mouse BTLA. A human BTLA variant lacking the transmembrane domain has been reported. | | | Catalog # | B5001-61C | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Absorption | 488nm | | Emission | 565-605nm | | Storage and Stability | May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Mouse | | Concentration | As reported | | Form | Supplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE). | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant human B and T Lymphocyte Attenuator (rhBTLA; aa5-150 with V105M, S138G, and M148V substitutions) expressed in NSO cells (Q7Z6A9). | | Specificity | Recognizes mouse BTLA. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
