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Anti -CD88 (C5aR, C5a Receptor 1, C5aR1, Complement Component 5a Receptor 1)
Anti -CD88 (C5aR, C5a Receptor 1, C5aR1, Complement Component 5a Receptor 1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
IP IH FC |
|
| The human anaphylatoxin C5a is a 74-residue glycopolypeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. A variety of biological effects evoked by C5a could be demonstrated, rendering this molecule an important mediator of inflammation, with granulocytes and macrophages as the main target cells. All cellular responses to C5a are specifically mediated by interactions with the membrane bound C5a receptor, a seven transmembrane GTPbinding-protein-coupled receptor that belongs to the rhodopsin supergene family. The C5a receptor is approximately 45kD. | | | Catalog # | C0012-01D | | Cellular Localization | Integral membrane protein. | | Applications | Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 8J452 | | Host | Mouse | | Concentration | ~0.1mg/ml | | Form | PBS, 0.1% BSA | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Unfortunately, this information is considered to be commercially sensitive, (extracellular domain of the N-terminus). | | Specificity | Species Crossreactivity: Crossreacts with Human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Anaphylatoxin Receptor |
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