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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -Caveolin 1 (Caveolin-1, CAV 1, CAV1, CAV-1, CAV, Caveolae Protein 22kD, Cell Growth-inhibiting Protein 32)

Anti -Caveolin 1 (Caveolin-1, CAV 1, CAV1, CAV-1, CAV, Caveolae Protein 22kD, Cell
Growth-inhibiting Protein 32)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
Caveolin-1 is a palmitoylated 22kD membrane-associated protein in caveolae which are cholesterol-rich invaginations in the plasma membrane involved in vesicular transport and the regulation of lipid rafts and signal transduction. Caveolin-1 expression is dysregulated during cancer progression and exhibits both positive and negative effects on tumor progression. The central region of Caveolin-1 (aa105-125) is buried in the lipid layer, while the N- and C-terminal flanking regions are exposed to the cytoplasm and interact with many other proteins. Alternate splicing in human, mouse, and rat Caveolin-1 generates an isoform with a deletion of the N-terminal 31 residues.
Catalog #C2097-90C
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: 0.2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS, 0.02% sodium azide. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with sterile PBS, 0.02% sodium chloride.
PurityPurified by immunoaffinity chromatography.
ImmunogenE.coli-derived recombinant human Caveolin-1 (rhCaveolin-1; aa1-104; Accession # Q03135).
SpecificityRecognizes human Caveolin-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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