Suitable for use in Western Blot, Immunoprecipitation and Antigen Capture Assay. Other applications not tested.
Recommended Dilutions
Western Blot: 1:20 Immunoprecipitation: 1:20 Antigen Capture Assay: 1:20 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Human platelets
Form
Supplied as a liquid in PBS, 0.05% sodium azide.
Purity
Purified
Specificity
Recognizes the human CD41b (GPIIb) subunit.
References
1. Autoantibodies against platelet glycoprotein Ib/IX: a frequent finding in autoimmune thrombocytopenic purpura: V. Kiefel, et al.; Br. J. Haematol. 79, 256 (1991) |2. A point mutation leads to an unpaired cysteine residue and a molecular weight polymorphism of a functional platelet beta 3 integrin subunit. The Sra alloantigen system of GPIIIa: S. Santoso, et al.; J. Biol. Chem. 269, 8439 (1994)
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