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Anti -CD49c (Integrin alpha3, Very Late Antigen3a chain, VLA3a)
Anti -CD49c (Integrin alpha3, Very Late Antigen3a chain, VLA3a)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
IH FC |
|
| Catalog # | C2404-08C | | Applications | Suitable for use in Flow Cytometry, Inhibition and Immunohistochemistry. Other aapplications not tested. | | Recommended Dilutions | Inhibition: Inhibits SCC9 cell adhesion to human and EHS laminin, but not laminin peptide GD-2. Potentiates inhibition of SKOV-3 cell adhesion to EHS laminin by anti-integrin alpha 5 antibody GoH3. Does not inhibit either cell’s adhesion to fibronectin or collagen type IV. | | Immunohistochemistry: On acetone-fixed frozen human epithelial tissues including tongue, foreskin and ovary. Not for use on formalin-fixed tissue. | | Flow cytometry: Stains human squamous cell carcinoma (SCC9), ovarian carcinoma (SKOV-3) and umbilical vein endothelial cells (HUVEC). | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | | | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 2Q994 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS pH 7.6, 0.1% sodium azide. | | Purity | Purified by Protein A chromatography. | | Immunogen | Human squamous cell carcinoma cells (SCC9). | | Specificity | Recognizes human alpha-3 integrin (CD49c). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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