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C2405-17E Mouse Anti-CD49d (Integrin alpha4, VLA4, LHR, Lymphocyte Homing Receptor)

Specifications
Clone Type
Monoclonal
Host
Mouse
Source
Human
Swiss Prot
P11215
Isotype
IgG1
Clone Number
2Q978 (P1H4)
Grade
Affinity Purified
Applications
E FC IC IHC IP RIA WB
Crossreactivity
Hu
Accession #
NM_000632.3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Notes
Preservative Free

The involvement of integrins in vascular proliferation, adhesion, and wound repair has been well-documented. The integrin family of cell adhesion receptors consists of at least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The structure and functional diversity of the integrin family are based upon the pairing abilities of the individual alpha and beta subunits.

Applications
Suitable for use in Immunohistochemistry, Immunocytochemistry, Immunoprecipitation, ELISA, FACS and RIA. Other applications have not been tested.
Recommended Dilution
Immunohistochemistry: Acetone and alcohol fixatives. Optimal dilutions to be determined by the researcher.
Biological Activity
Inhibits CS-1 and VCAM binding.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Human T lymphocytes.
Form
Supplied as a liquid in 0.01M PBS, pH 7.1, 0.15M sodium chloride. No preservative added.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human and primate integrin alpha 4.
Conjugates
Pricing
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