Anti -Chlamydia trachomatis MOMP (Major Outer Membrane Protein) (Azide Free)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Ascites |
E |
|
| Chlamydia is caused by the bacterium Chlamydia trachomatis. The intracytoplasmic inclusions caused by the bacterium are draped around the infected cell’s nucleus. The Chlamydia genome contains 500-100 kilobases of both DNA and RNA. The organism is also extremely temperature sensitive and must be refrigerated at 4°C as soon as a sample is obtained. Colonization of Chlamydia begins with attachment to sialic acid receptors on the eye, throat or genitalia. Infection persists at body sites that are inaccessible to phagocytes, T-cells, and B-cells. There are 15 separate Chlamydia serotypes that are the etiologic agents of 4 major diseases in humans: endemic trachoma (caused by serotypes A and C), sexually transmitted disease and inclusion conjunctivitis (caused by serotypes D and K), and lymphogranuloma venereum (caused by serotypes L1, L2, and L3). The Chlamydial cell wall inhibits phagolysosome fusion in phagocytes. The cell wall contains an outer lipopolysaccharide membrane, but no peptidoglycan. The absence of peptidoglycan is inferred because muramic acid is not detectable. There is a possibility that other carboxylated sugars are present. The proposed structure of the cell wall is that of a major outer membrane protein, cross-linked with disulfide bonds ,with many cysteine-rich proteins (CRP). CRP’s may be the functional equivalent to peptidoglycan. This unique structure allows for intracellular division and extracellular survival. | | | Catalog # | C4250-61X | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add glycerol (25–50%) and freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a,k | | Clone No | 1.B.194 | | Host | Mouse | | Concentration | Not determined | | Form | Supplied as ascites. No preservative added. | | Purity | Ascites | | Immunogen | Chlamydia elementary bodies | | Specificity | Reactive with the following serovars: A, B, Ba, C, D, E, F, G, H, I, J, K, L1, L2, L3 | | | Important Note | This product is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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