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Anti -Clara Cell Protein (CC16, CC10, Uteroglobin, Urinary Protein 1, Clara Cell Secretory Protein)
Anti -Clara Cell Protein (CC16, CC10, Uteroglobin, Urinary Protein 1, Clara Cell Secretory
Protein)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
E B IH |
|
| Uteroglobin, previously called CCPBP, CC10 or blastokinin, is a small secreted protein of the secretoglobin (family 1A, member 1). Uteroglobin is expressed by Clara cells, the non-ciliated, non-mucous secretory cells predominant in lung bronchioles, and by other epithelia that communicate with the external environment. Uteroglobin binds to phospholipids and to several cell types, inhibiting inflammation, migration and invasion. It has been reported to bind the lipocalin-1 receptor. The mature 70aa protein forms a disulfide-linked heterodimer of 16kD. | | | Catalog # | C5828-01A | | Applications | Suitable for use in Immunohistochemistry, Western Blot and ELISA. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry: 15ug/ml with basic antigen retrieval in paraffin-embedded normal human lung tissue sections. | | Western Blot: 1-2ug/ml. Using colorimetric detection system, the detection limit is ~5ng/lane under non-reducing and reducing conditions. ECL detection will increase sensitivity by 5-50x fold. | | Direct ELISA: 0.5-1ug/ml. The detection limit is ~5ng/well. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 7H197 | | Host | Rat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | E. coli-derived recombinant human Uteroglobin (aa22-91, Accession #NP_003348). | | Specificity | Recognizes human Clara Cell Protein. Species Sequence Homology: mouse, 53% | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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