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Anti -Collagen Type VI
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Ascites |
IP IH Gel |
|
| The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha 1(VI), alpha 2(VI), and alpha 3(VI) chains. Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. | | | Catalog # | C7510-60F | | Applications | Suitable for use in Immunohistochemistry, Immunoprecipitation and Dot Blot. Other applications have not been tested. | | Recommended Dilutions | Immunohistochemistry: Cyostat sections fixed with either acetone or 4% formaldehyde. Not tested on paraffin embedded tissues. | | Optimal dilution determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgM | | Clone No | 2Q638 | | Host | Mouse | | Source | Human | | Concentration | Not Determined | | Form | Supplied as a liquid. | | Purity | Ascites | | Immunogen | SDS-insoluble extracts of human colon tissue. | | Specificity | Recognizes human collagen type VI. Specificity established by identical reaction in immunoprecipitation of labeled lysates of human osteosarcoma cells MG63 with a reference monclonal antibody to type VI collagen. Precipitates a 140kD band and some dimers. Stains stroma of different organs with a pattern identical to that of the reference antibody. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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