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You are here:Home » Antibodies » Abs to Collagen » Anti -Collagen Type VI

Anti -Collagen Type VI

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites IP IH
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha 1(VI), alpha 2(VI), and alpha 3(VI) chains. Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Catalog #C7510-60F
ApplicationsSuitable for use in Immunohistochemistry, Immunoprecipitation and Dot Blot. Other applications have not been tested.
Recommended DilutionsImmunohistochemistry: Cyostat sections fixed with either acetone or 4% formaldehyde. Not tested on paraffin embedded tissues.
Optimal dilution determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgM
Clone No2Q638
HostMouse
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid.
PurityAscites
ImmunogenSDS-insoluble extracts of human colon tissue.
SpecificityRecognizes human collagen type VI. Specificity established by identical reaction in immunoprecipitation of labeled lysates of human osteosarcoma cells MG63 with a reference monclonal antibody to type VI collagen. Precipitates a 140kD band and some dimers. Stains stroma of different organs with a pattern identical to that of the reference antibody.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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