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You are here:Home » Antibodies » Abs to Connexin, Junction Proteins » Anti -Connexin 43 (Cx43, Gap Junction Alpha 1 Protein, CxA-1)

Anti -Connexin 43 (Cx43, Gap Junction Alpha 1 Protein, CxA-1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The connexins are a group of gap junction proteins which form a hexamer to compose a connexon. Clusters of connexons form a gap junction through which low molecular weight proteins may diffuse from cell to cell. Connexins are also thought to be essential for the development of labor contractions.
Catalog #C7857-10
ApplicationsSuiitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: Ab 2-4ug/ml for 2 hours at RT. Optimal dilutions to be determined by the researcher.
Positive Control Heart
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceRat
Concentration~0.2mg/ml
FormSupplied as a liquid in 10mM PBS, pH 7.6, 0.2% BSA and 15mM sodium azide before the addition of glycerol to 40%.
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide corresponding to a segment of the 3rd cytoplasmic domain of rat connexin 43.
Cellular LocalizationCytoplasmic. MW of Antigen: 43kD
SpecificityRecognizes human Connexin 43.
Species CrossreactivityMouse and Rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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