Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -COX4 (Cytochrome C Oxidase Subunit 4, COXIV)

Anti -COX4 (Cytochrome C Oxidase Subunit 4, COXIV)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B
Cytochrome c oxidase (COX) is a hetero- oligomeric enzyme consisting of 13 subunits localized to the inner mitochondrial membrane (1-3). It is the terminal enzyme complex in the respiratory chain, catalyzing the reduction of molecular oxygen to water coupled to the translocation of protons across the mitochondrial inner membrane to drive ATP synthesis. The 3 largest subunits forming the catalytic core are encoded by mitochondrial DNA while the other smaller subunits, including COX IV, are nuclear-encoded. Deficiency in COX activity has been correlated with a
number of human diseases (4). The COX IV antibody can be used effectively as a mitochondrial loading control.
Catalog #C7904-89E1
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No10E16
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as liquid in PBS, pH 7.4, 2mg/ml BSA, 50% glycerol. Labeled with HRP.
PuritySupernatant
ImmunogenA synthetic peptide corresponding to residues surrounding Lys29 of human COX IV (KLH).
SpecificityRecognizes endogenous levels of human total COX IV protein. Species Crossreactivity: monkey.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links