Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Molecular Biology » MB-Cardiac Markers » C-Reactive Protein, 95-98%, Concentrated (CRP, MGC88244, PTX 1, PTX1)

C-Reactive Protein, 95-98%, Concentrated (CRP, MGC88244, PTX 1, PTX1)


  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.


C-reactive protein (CRP) is an acute phase reactant. CRP is released by the body in response to acute injury, infection, or other inflammatory stimuli. Recent development of a high sensitivity assay for CRP (hs-CRP) has enabled investigation of this marker of systemic inflammation.
Catalog #C7907-26A
CRP and AtherosclerosisAtheromatous plaques in diseased arteries typically contain inflammatory cells. Rupture of atheromatous plaque is thought to be the mechanism for acute myocardial infarction and acute coronary syndrome. The most common site of plaque rupture appears to be the shoulder region where inflammatory cells are most prominent. Thus the release of acute phase reactants as a response to inflammation have been proposed as a potential marker of an "unstable" atheromatous plaque and underlying atherosclerosis.
Studies have shown a positive association between CRP and coronary artery disease. In a survey of 388 British men aged 50-69, the prevalence of coronary artery disease increased 1.5 fold for each doubling of CRP level (Mendall MA, Patel P, Ballam L, et al. C-reactive protein and its relation to cardiovascular risk factor A population based cross sectional study. BMJ. 1996;312:1061-1065.)
Multiple prospective studies have also demonstrated that baseline CRP is a good marker of future cardiovascular events (Riker P, Haughie P. Prospective studies of C-reactive protein as a risk factor for cardiovascular disease. J Investig Med. 1998;46391-395.)
CRP may be a good marker of cardiovascular risk in addition to lipid level.
ApplicationSuitable for antigenic use in immunological protocols.
Recommended DilutionsOptimal dilutions to be determined by researcher.
Storage & StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and freeze at -20°C. Aliquots are stable for 6 months after receipt at -20°C. Further dilutions can be made in assay buffer.
Molecular Weight21kD
SourceHuman Pleural/Ascites Fluids
PurityHighly purified (~95%, RID Behring, SDS-PAGE). Sterile Filtrered (0.2um). Single band at 21kD.
FormSupplied as a liquid in TBS, pH 7.4. No preservative added.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

External Links