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You are here:Home » Antibodies » Abs to Nucleotides » Anti -Cyclic GMP (cGMP)

Anti -Cyclic GMP (cGMP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
Catalog #C8450-25A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:4000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Also AvailableC8450-25A: Cyclic GMP (cGMP) Pab Rb x
C8450-25B: Cyclic GMP (cGMP) Pab Rb x
C8450-25C: Cyclic GMP (cGMP) Pab Rb x
Clone TypePolyclonal
IsotypeIgG
HostRabbit
ConcentrationNot determined
FormSupplied as a liquid in PBS, 0.1% sodium azide
PuritySerum
ImmunogenCyclic GMP (cGMP)
SpecificityRecognizes cGMP
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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