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C8452-06C Mouse Anti-Cyclin A2 (Cyclin-A2, CCNA2, CCN1, Cyclin-A, CCNA)

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Isotype
IgG2a
Clone Number
E23.1
Grade
Affinity Purified
Applications
WB
Crossreactivity
Bo Hu Mo
Shipping Temp
Blue Ice
Storage Temp
-20°C

Cyclins regulate the activity of the Cyclin-dependent protein kinases. Cyclin A is involved in the regulation of the cell cycle and seems to be essiential for S phase and M phase. Studies have shown that overexpression of cyclin A can accelerate the G1 to S phase. Cyclin A is a marker for actively proliferating cells and for cells in S phase.

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 0.5-1ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Cyclin A fusion protein
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by affinity chromatography.
Specificity
Recognizes Cyclin A. Species Crossreactivity: human, mouse and bovine.
References
1. Pagano M et al. 1992. EMBO J 11:961. 2. Geley S et al. 2001 J Cell Biol. 153:137. 3. Resinitzky D et al. 1995. Mol Cell Biol 15:4347. 4. Furuno N et al. 1999. J Cell Biol. 147:295.
USBio References
No references available
Conjugates
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