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You are here:Home » Antibodies » Abs to Cyclin » Anti -Cyclin E1

Anti -Cyclin E1

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Cyclin E1 is a protein (approx. 50 kD) expressed in elevated levels in human tumor cells. It controls the initiation of DNA synthesis by activating cdk2, and expression of cyclin E1 is upregulated by the E7 oncoprotein.
Catalog #C8455-26E
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa43-52 of polyclonal human Cyclin E1
SpecificityRecognizes human Cyclin E1. Cyclin E1 expression is elevated in human tumor cells. Reacts with residues 43-52 [GSQPWDNNAVC] of Cyclin E1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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