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You are here:Home » Antibodies » Abs to Receptors, Tyrosine Kinase » Anti -DDR1 (Discoidin Domain Receptor Tyrosine Kinase 1, Epithelial Discoidin Domain-containing Receptor 1, Epithelial Discoidin Domain Receptor 1, EDDR1, CD167 Antigen-like Family Member A, CD167a, CD167, Cell Adhesion Kinase, CAK, DDR, Discoidin Receptor Tyro

Anti -DDR1 (Discoidin Domain Receptor Tyrosine Kinase 1, Epithelial Discoidin
Domain-containing Receptor 1, Epithelial Discoidin Domain Receptor 1, EDDR1, CD167
Antigen-like Family Member A, CD167a, CD167, Cell Adhesion Kinase, CAK, DDR, Discoidin
Receptor Tyro

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Purified B IP IF
The discoidin domain receptors (DDRs) are receptor tyrosine kinases with a discoidin homology
repeat in their extracellular domains, activated by binding to extracellular matrix collagens. So far, two mammalian DDRs have been identified: DDR1 and DDR2 (1). They are widely expressed in human tissues and may have roles in smooth muscle cell-mediated collagen remodeling (2). Aberrant expression and signaling of DDRs have been implicated in human disease related to increased matrix degradation and remodeling, such as cardiovascular disease, liver fibrosis,
and tumor invasion (1).
Catalog #D1649-03G
ApplicationsSuitable for use in Immunofluorescence, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence (IF-IC): 1:800
Western Blot: 1:1000 Incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight.
Immunoprecipitation: 1:100
Immunohistochemistry (FFPE): 1:6400 using citrate buffer retrieval.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG
Clone No11C1024
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, <0.02% sodium azide, 50% glycerol.
PurityPurified
ImmunogenSynthetic peptide corresponding to residues surrounding Pro600 of human DDR1.
SpecificityRecognizes endogeneous levels of total human DDR1. Species Crossreactivity: monkey, mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=2.7.10.1


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