Anti -DDR1 (Discoidin Domain Receptor Tyrosine Kinase 1, Epithelial Discoidin
Domain-containing Receptor 1, Epithelial Discoidin Domain Receptor 1, EDDR1, CD167
Antigen-like Family Member A, CD167a, CD167, Cell Adhesion Kinase, CAK, DDR, Discoidin
Receptor Tyro
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Purified |
B IP IF |
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| The discoidin domain receptors (DDRs) are receptor tyrosine kinases with a discoidin homology | | | repeat in their extracellular domains, activated by binding to extracellular matrix collagens. So far, two mammalian DDRs have been identified: DDR1 and DDR2 (1). They are widely expressed in human tissues and may have roles in smooth muscle cell-mediated collagen remodeling (2). Aberrant expression and signaling of DDRs have been implicated in human disease related to increased matrix degradation and remodeling, such as cardiovascular disease, liver fibrosis, | | | and tumor invasion (1). | | | Catalog # | D1649-03G | | Applications | Suitable for use in Immunofluorescence, Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Immunofluorescence (IF-IC): 1:800 | | Western Blot: 1:1000 Incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight. | | Immunoprecipitation: 1:100 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 11C1024 | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 100ug/ml BSA,less than 0.02% sodium azide, 50% glycerol. | | Purity | Purified | | Immunogen | Synthetic peptide corresponding to residues surrounding Pro600 of human DDR1. | | Specificity | Recognizes endogeneous levels of total DDR1. Species Crossreactivity: monkey, mouse, rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | EC=2.7.10.1 |
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Download Specifications for Anti -DDR1 (Discoidin Domain Receptor Tyrosine Kinase 1, Epithelial Discoidin Domain-containing Receptor 1, Epithelial Discoidin Domain Receptor 1, EDDR1, CD167 Antigen-like Family Member A, CD167a, CD167, Cell Adhesion Kinase, CAK, DDR, Discoidin Receptor Tyro |
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