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You are here:Home » Antibodies » Abs to Protein Kinase Inhibitors » Anti -IKBB, CT (NFKBIB, NF-kappa-B Inhibitor beta, NF-kappa-BIB, I-kappa-B-beta, IkB-B, IkB-beta, IkappaBbeta, Thyroid Receptor-interacting Protein 9, TR-interacting Protein 9, TRIP-9, TRIP9)

Anti -IKBB, CT (NFKBIB, NF-kappa-B Inhibitor beta, NF-kappa-BIB, I-kappa-B-beta, IkB-B,
IkB-beta, IkappaBbeta, Thyroid Receptor-interacting Protein 9, TR-interacting Protein 9,
TRIP-9, TRIP9)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E B IP IH IF
NFkB exists in the cytoplasm as a complex with a 38kD inhibitor protein, IkB (MAD-3). Activation of NFkB by different stimuli, including TNFa and PMA, requires the dissociation of the inhibitor protein. Dissociation is regulated by the phosphorylation of IkB on serine residues 32 and 36 which targets IkB for ubiquinitation and proteasome mediated degradation. The NFkB complex then translocates to the nucleus and activates transcription of responsive genes.
Catalog #I2500-09G
ApplicationsSuitable for use in Immunofluorescence, ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid.
PuritySerum
ImmunogenSynthetic peptide corresponding to human NFKBIB at C-terminal (KLH).
SpecificityRecognizes human NFKBIB.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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