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Anti -Interleukin 1 beta (IL-1b) (Azide Free)
Anti -Interleukin 1 beta (IL-1b) (Azide Free)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
E N |
|
| IL-1 beta is produced by activated macrophages. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell matur- ation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stim- ulate the release of prostaglandin and collagenase from syn- ovial cells. IL-1beta is a monomeric secreted protein that may be released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. | | | Catalog # | I7663-11A2 | | Applications | Suitable for use in ELISA and Neutralization. Other applications not tested. | | Recommended Dilution | Sandwich ELISA: 10pg/ml-3ng/ml after zymosan induced inflammation (2). Can be used as the capture reagent in a two-site sandwich ELISA for measuring mouse IL-1b levels using recombinant mouse IL-1b as the standard. | | Optimal dilution to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 4H130 | | Host | Rat | | Source | Mouse | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS. Azide-free. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Mouse Interleukin 1 beta . | | Specificity | Recognizes both the recombinant and the natural form of mouse IL-1b. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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