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Anti -Interleukin 6 Receptor (CD126, IL-6R)
Anti -Interleukin 6 Receptor (CD126, IL-6R)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
IC FC |
|
| IL-6 R, also known as CD126, is a transmembrane protein that associates with the signal-transducing subunit gp130 to form a high-affinity receptor complex for IL-6. It is expressed on T cells, activated B cells, and peripheral monocytes. A soluble form of IL-6 R can be released by proteolytic cleavage. | | | Catalog # | I8428-39M | | Applications | Suitable for use in Flow Cytometry and Immunocytochemistry. Other applications not tested. | | Recommended Dilutions | Flow Cytometry: 2.5ug/10e6 cells using mouse CD3+ splenocytes | | Immunocytochemistry: 8-25ug/ml using immersion fixed mouse splenocytes | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 8H130 | | Host | Rat | | Source | Mouse | | Concentration | ~0.5mg/ml (after reconstitution) | | Form | Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 1ml sterile PBS. | | Purity | Purified by Protein G affinity chromatography | | Immunogen | Recombinant protein corresponding to aa20-357 from mouse IL-6R expressed in NSO cells (P22272). | | Specificity | Recognizes mouse IL-6R. Does not crossreact with rhIL-6R. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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