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You are here:Home » Antibodies » Abs to Motor Proteins » Anti -Kinesin 2 (Kinesin-2, KNS2, HK2, KIF2, KIF2A, Kinesin Heavy Chain Member 2, Kinesin-like Protein KIF2A, Kinesin Heavy Chain Member 2A)

Anti -Kinesin 2 (Kinesin-2, KNS2, HK2, KIF2, KIF2A, Kinesin Heavy Chain Member 2,
Kinesin-like Protein KIF2A, Kinesin Heavy Chain Member 2A)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IH
Kinesin heavy chain member 2 is a kinesin-like motor protein. The kinesin-related proteins are involved in functions related to movements of organelles, microtubules, or chromosomes along microtubules. These functions include axonal transport, microtubule sliding during nuclear fusion or division, and chromosome disjunction during meiosis and early mitosis. The kinesins are tetramers composed of 2 heavy and 2 light chains. The N-terminal heavy chain sequences show similarity in all the kinesin-related proteins. The N-terminal part forms the motor domain, with the microtubule-binding region allowing the protein to slide along the microtubule. It also possesses an ATP-binding site allowing an ATPase activity that provides the energy required for the movement. Kinesin-like motor proteins are found in several vertebrate cell types but is strongly expressed in neuronal cells. In dividing cells it is required for bipolar spindle formation and chromosome segregation. In neuronal cells it is involved in neurite outgrowth.
Catalog #K1781-01A
ApplicationsSuitable for use in ELISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1, k
Clone No2D4
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified.
ImmunogenKIF2 (AAH31828, 1-680aa) full length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human KIF2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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