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You are here:Home » Antibodies » Antibodies-Cell Markers » Anti -Mast Cell Chymase (Biotin)

Anti -Mast Cell Chymase (Biotin)


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Clone Host Grade Applications
Monoclonal Mouse Highly Purified IH IC
Mast cell chymase (EC, a member of the granzyme subfamily of the S1 family of peptidases, cleaves chymase C-terminal to Phenylalanine, Tyrosine, Tryptophan, and Leucine residues (in order of preference). Chymase is stored in mast cell granules within the cell and is the major secreated mast cell protease. Secreated mast cell chymase is believed to be involved in extracellular matrix degradation, vasoactive peptide generation, and regulation of gland secreation.
Catalog #M2414-01
ApplicationsSuitable for use in Immunohistochemistry and Immunocytochemistry. Not recommended for Western Blot. Other applications have not been tested.
Recommended DilutionsImmunohistochemistry/Immunocytochemistry: 0.5-1ug/ml; For optimal results, tissues or cytospin preparations should be fixed in Carnoy’s Fluid (60% ethanol, 30% chloroform, 10% glacial acetic acid). Not recommended for use on formaldehyde fixed tissue.
Optimal dilutions to be determined by the researcher.
SourceCulture Supernatant
Positive ControlLung, Heart, Skin, Placenta
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No2Q1506
FormSupplied as a liquid in PBS, pH 7.1, 15mg/ml BSA, 0.09% sodium azide. Labeled with Biotin.
PurityPurified by ammonium sulfate precipitation and DEAE-Sephacyl chromatography.
ImmunogenChymase purified from human skin.
SpecificityRecognizes human mast cell chymase.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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