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MEK1 Inhibitor (PD98059, 2’-amino-3’-methoxyflavone)
MEK1 Inhibitor (PD98059, 2’-amino-3’-methoxyflavone)
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| Potent, selective and cell-permeable inhibitor of MAP kinase kinase (also known as MAPK/ERK kinase or MEK kinase). Inhibits phosphorylation of MAP kinase by MAP kinase kinase. PD 98059 does not inhibit MAP kinase itself. IC50 values for PD 98059-induced effects are in the 1-20uM range for many assays; it is somewhat weaker in inhibiting cell growth in monolayers or agar for some cell lines. | | | Catalog # | M2865-17C | | Solubility | Soluble in DMSO. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | 167869-21-8 | | Molecular Formula | C16H13NO3 | | Molecular Weight | 267.28 | | Purity | ~99% | | Form | Supplied as a pale yellow powder. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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