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Anti -MERTK, CT (Tyrosine-protein Kinase Mer, Proto-oncogene c-Mer, Receptor Tyrosine Kinase MerTK, MER)
Anti -MERTK, CT (Tyrosine-protein Kinase Mer, Proto-oncogene c-Mer, Receptor Tyrosine
Kinase MerTK, MER)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E IH |
|
| Mer, an Axl type tyrosine kinase, contains a cell adhesion molecule-related extracellular domain. Mutation of Mer results in defective phagocytosis of photoreceptor outer segments by the retinal pigment epithelium (RPE) and retinal degeneration. In addition, Mer has been suggested to be critical for the engulfment and efficient clearance of apoptotic cells. This has implications for inflammation and autoimmune diseases such as systemic lupus erythematosus. | | | Catalog # | M2995-06A | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:2000 | | Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide C-DSSEGSEVLM from the C-terminus of human MERTK. | | Specificity | Recognizes human MERTK. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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