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You are here:Home » Antibodies » Antibodies-MHC » Anti -MHC Class 1 HLA ABC

Anti -MHC Class 1 HLA ABC


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IH
Human MHC class I antigens (HLA-A, B and C) are expressed constitutively on all nucleated cells such as lymphocytes, thymocytes, granulocytes, and bone marrow cells. They are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
Catalog #M3886-12
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry: Frozen only. Acetone fixation recommended.
Optimal dilutions to be determined by the researcher.
Positive ControlHuman lymphocytes. Tonsil and lymph node.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No3F273
FormSupplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide. Also available without BSA and azide. See M3886-12X.
PurityPurified by Protein A affinity chromatography.
ImmunogenCell membranes of human tonsil lymphocytes.
SpecificityRecognizes a monomorphic determinant of human major histocompatibility (MHC) class I antigens.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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