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You are here:Home » Antibodies » Abs to MHC » Anti -MHC Class 1 HLA ABC

Anti -MHC Class 1 HLA ABC

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IH
Human MHC class I antigens (HLA-A, B and C) are expressed constitutively on all nucleated cells such as lymphocytes, thymocytes, granulocytes, and bone marrow cells. They are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
Catalog #M3886-12
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry: Frozen only. Acetone fixation recommended.
Optimal dilutions to be determined by the researcher.
Positive ControlHuman lymphocytes. Tonsil and lymph node.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No3F273
HostMouse
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide. Also available without BSA and azide. See M3886-12X.
PurityPurified by Protein A affinity chromatography.
ImmunogenCell membranes of human tonsil lymphocytes.
SpecificityRecognizes a monomorphic determinant of human major histocompatibility (MHC) class I antigens.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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