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You are here:Home » Antibodies » Abs to MHC » Anti -MHC Class 1 Chain-related Gene A (MHC Class I Polypeptide-related Sequence A, MICA, MIC-A, PERB11.1)

Anti -MHC Class 1 Chain-related Gene A (MHC Class I Polypeptide-related Sequence A, MICA,
MIC-A, PERB11.1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
MICA and MICB are stress inducible antigens, which are closely related and appear functionally indistinguishable. MICA and MICB are ligands for NKG2D, an activating receptor expressed by most natural killer (NK) cells, CD8 T cells and gamma/delta T-cells. Research indicates that the MICA/NKG2D interaction may stimulate anti-tumor reactivity by T-lymphocytes.
Catalog #M3886-75E
MICA is widely expressed in normal tissues, except those of the nervous system, and on many tumors. Expression levels of MICA may be increased by heat shock, oxidative stress, and virus infection.
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to a 16 amino acid peptide located near the C-terminal region of human MICA.
SpecificityRecognizes the human MHC class I chain-related protein A (MICA), a cell surface protein belonging to the MIC family.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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