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You are here:Home » Antibodies » Abs to Myelin » Anti -Myelin, Degenerating

Anti -Myelin, Degenerating

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
Can specifically detect demyelinating lesions in brains with multiple sclerosis, multiple system atrophy (MSA), as well as infarcted brains. The antibody is, therefore, a very useful tool for detecting demyelination but not myelin in normal brain.
Catalog #M9757-03A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No8A138
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide of QDENPVV corresponding to human (h) myelin basic protein (MBP) residues 215 to 221
SpecificityRecognizes degenerating myelin in multiple sclerosis and multiple system atrophy (MSA), but not myelin in normal brain.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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