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Anti -MYRIP, CT (Rab Effector MyRIP, Exophilin-8, Myosin-VIIa- and Rab-interacting Protein, Slp Homolog Lacking C2 Domains c, SlaC2-c, SLAC2C)
Anti -MYRIP, CT (Rab Effector MyRIP, Exophilin-8, Myosin-VIIa- and Rab-interacting Protein, Slp Homolog Lacking C2 Domains c, SlaC2-c, SLAC2C)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B IH |
|
| A molecular complex composed of Rab27A, MYRIP and myosin VIIa bridges retinal melanosomes to the actin cytoskeleton and thereby mediates the local trafficking of these organelles. The defect of this molecular complex is likely to account for the perinuclear mislocalization of the melanosomes observed in the retinal pigment epithelium cells of myosin VIIa-defective mice. | | | Catalog # | M9931-25C | | Applications | Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:64,000 | | Western Blot: 1:64,000 & 0.1-0.3ug/ml | | Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | | | Immunogen | Synthetic peptide corresponding to C-KDLMEPALESAVMY of human MYRIP at C-terminal. | | Specificity | Recognizes human MYRIP. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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