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P3050 D-Pantothenic Acid, Sodium Salt (Vitamin B5) CAS: 867-81-2

Specifications
References
CAS Number
867-81-2
Grade
Cell Culture Grade
MDL Number
MFCD00002767
Molecular Formula
C9H16NO5Na
Molecular Weight
241.22
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
Sodium D-Pantothenate; N-[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]-β-alanine, monosodium salt; Pantothenic acid, monosodium salt; Sodium pantothenic acid

Pantothenic acid (vitamin B5) is a precursor in the biosynthesis of coenzyme A, which is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Two enantiomers of pantothenic acid exist, D- or L-form. D-Pantothenic acid (sodium salt) is a sodium salt form of the biologically active enantiomer of vitamin B5 and is used in the synthesis of coenzyme A. The L-form of pantothenic acid is biologically inactive and has been shown to act as an antagonist of D-pantothenic acid.

Synonyms
Sodium D-Pantothenate; N-[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]-β-alanine, monosodium salt; Pantothenic acid, monosodium salt; Sodium pantothenic acid
CAS No
867-81-2
Molecular Formula
C9H16NO5Na
Molecular Weight
241.22
Purity (TLC)
≥98%
Appearance
White, crystalline powder
Solubility (400mg/4ml H2O)
Colorless, clear to slight haze
Method for Determining Identity
Proton NMR and Mass Spectroscopic Analysis
Storage and Stability
Store at 4°C under inert atmosphere. Hygroscopic! Heat sensitive!.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Jackowski, S. Biosynthesis of pantothenic acid and coenzyme A., Chapter 44, in Escherichia coli and Salmonella typhimurium: Cellular and molecular biology. Neidhardt, F.C., Curtiss, R., Gross, C.A. et al., editors, editors, American Society for Microbiology, Washington D.C., 687-694 (1996).|2. Leonardi, R., Zhang, Y.-M., Rock, C.O., et al. Coenzyme A: Back in action. Prog. Lipid Res. 44(2-3), 125-153 (2005).|3. Shibata, K., Kaneko, M., and Fukuwatari, T. D-pantethine has vitamin activity equivalent to D-pantothenic acids for recovering from a deficiency of D-pantothenic acid in rats. J. Nutr. Sci. Vitaminol. (Tokyo) 59(2), 93-99 (2013).|4. Kimura, S., Furukawa, Y., Wakasugi, J., et al. Antagonism of L(-)pantothenic acid on lipid metabolism in animals. J. Nutr. Sci. Vitaminol. (Tokyo) 26(2), 113-117 (1980).
USBio References
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