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You are here:Home » Antibodies » Abs to Ubiquitin Ligases » Anti -Parkin (Ubiquitin-protein Ligase E3) (epitope a)

Anti -Parkin (Ubiquitin-protein Ligase E3) (epitope a)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Parkin is a ubiquitin-protein ligase (E3) involved in the ubiquitin proteasomal pathway by participating in the removal of abnormally folded or damage protein. It is highly expressed in the brain, including the substancia nigra, and is also expressed in other tissues (heart, testis, skeletal muscle). Mutations in the parkin gene causing loss of E3 activity are responsible for autosomal recessive juvenile Parkinson's desease.
Catalog #P3112-04
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide (RILGEEQYNRYQQYGAEEC) corresponding to aa305-323 of human Parkin
SpecificityRecognizes human Parkin
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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