HIWI, also called PIWIL1 is an 861aa, 99kD (predicted) cytoplasmic protein of the PIWI subgroup of the Argonaute family. PIWI domains bind a class of ~29-30 nucleotide RNAs termed piRNAs. PIWIL1 orthologs are expressed with piRNAs in germ cells and are essential for spermatogenesis in mice. CD34+ hematopoietic progenitor cell PIWIL1 is downregulated upon differentiation. When overexpressed in leukemic cell lines, PIWIL1 inhibits growth and induces apoptosis. Human PIWIL1 shares 95% aa sequence identity with mouse and rat PIWIL1.
| Product | Size | List | Your Price | Qty | Ext Price | ||||
|---|---|---|---|---|---|---|---|---|---|
| Subtotal: | Subtotal: | ||||||||
| Subtotal: | Subtotal: | ||||||||
| Total Coupon Savings: | Total Coupon Savings: | () | |||||||
| Your cart is currently empty. | |||||||||
| - Coupon Code | |||||||||
We accept the following payment methods as well as pay-by-invoice.
TDS
NCBI
UniProt
Tech Support
Customer Service
