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You are here:Home » Antibodies » Antibodies-Myelin » Anti -PMP 22 (Peripheral Myelin Protein 22, PMP22, PMP-22, Growth Arrest Specific 3, GAS3, HNPP, Trembler)

Anti -PMP 22 (Peripheral Myelin Protein 22, PMP22, PMP-22, Growth Arrest Specific 3, GAS3,
HNPP, Trembler)


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Clone Host Grade Applications
Monoclonal Mouse Purified IH
Peripheral Myelin Protein 22 (PMP22) is a 160 amino acid glycoprotein which is a member of the claudin family and is thought to play an important role in the structure of peripheral nerve myelin. Irregularities in its gene results in hereditary demyelinating neuropathies. PMP22 protein is present in the compact myelin of adult human peripheral nerve and its distribution mimics that of Myelin Protein zero (P0).
Suitable for use in Immunohistochemistry (paraffin). Other applications have not been tested
Recommended Dilutions:
Optimal dilutions to be determined by the researcher.
Catalog #P4305-04
Positive Control Fetal spinal cord
Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No8B92
FormSupplied as a liquid in Tris-glycine, 150mM NaCl, 0.05% sodium azide.
ImmunogenHuman PMP22 cDNA boosted with a 13-amino acid peptide of the 2nd extracellular domain (a.a. 120-133) conjugated to murine IgG. [Swiss-Prot# Q01453]. Localization: Membrane
SpecificityRecognizes human PMP 22. Species Crossreactivity: rhesus monkey. No reactivity with mouse, rat, or bovine nerve protein. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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