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Anti -PPARg (Peroxisome Proliferator Activated Receptor gamma, PPAR-gamma, Nuclear Receptor Subfamily 1 Group C Member 3, NR1C3, PPARG)
Anti -PPARg (Peroxisome Proliferator Activated Receptor gamma, PPAR-gamma, Nuclear
Receptor Subfamily 1 Group C Member 3, NR1C3, PPARG)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IH |
|
| Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a 57.6kD transcription factor belonging to the nuclear hormone receptor (NR1) family. PPARG is vital in the regulation of cellular differentiation, development and metabolism. PPARG is a key regulator of adipocyte differentiation and glucose homeostasis. In addition, PPARG is the main target of thiazolidinediones (TZDs), a class of drug used in diabetes mellitus and other diseases that feature insulin resistance. PPARG is widely expressed with high concentrations being found in adipose tissue. | | | Catalog # | P5505-06F | | Applications | Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:4,000 | | Western Blot: 1:1,000 | | Immunohistochemistry (paraffin): 2.5ug/ml | | Requires antigen retrieval using heat treatment for 20 minutes prior to staining of paraffin sections. 0.01 M sodium citrate buffer, pH 6.0 is recommended for this purpose. | | Optimal dilutions to be determined by the researcher. | | Positive Control Tissue | Human prostate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to a region near the amino terminus of human PPAR gamma 2. | | Specificity | Recognizes human Peroxisome proliferator-activated receptor gamma. Species crossreactivity: mouse, canine, porcine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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