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Abs to Transcription Factors, Zinc (Ring) Finger
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Anti -Prdm-1a, ID (PR Domain Containing 1a, with ZNF Domain, prdm1a, Dr.77773, prdm1)
Anti -Prdm-1a, ID (PR Domain Containing 1a, with ZNF Domain, prdm1a, Dr.77773, prdm1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
|
| PR domain containing 1a (prdm-1a) is a transcription factor essential for the specification of slow twitch muscle fibers that derive from adaxial cells in zebrafish. Prdm-1 acts as a transcriptional repressor in mediating the transcriptional repressor sox-6, which activates slow-twitch specific muscle gene expression. Zebrafish prdm-1 exhibits a dynamic and evolutionarily conserved expression pattern. Prdm-1 has been shown to be necessary for zebrafish forelimb development. The zebrafish narrowminded (nrd) mutation, which leads to absence of Rohon-Beard neurons and a reduction in neural crest cells and their derivatives, is a mutation in prdm-1. | | | Catalog # | P5750-01V | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:5000-1:20,000 | | Western Blot: 1:500-1:1000 | | Optimal dilutions to be determined by the researcher. | | Control Peptide | P5750-01Y | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Zebrafish | | Concentration | As reported | | Form | Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.05% sodium azide, 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to the intermediate region of zebrafish Prdm-1a. | | Specificity | Recognizes zebrafish Prdm-1a. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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