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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -Prdm-1a, ID (PR Domain Containing 1a, with ZNF Domain, prdm1a, Dr.77773, prdm1)

Anti -Prdm-1a, ID (PR Domain Containing 1a, with ZNF Domain, prdm1a, Dr.77773, prdm1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
PR domain containing 1a (prdm-1a) is a transcription factor essential for the specification of slow twitch muscle fibers that derive from adaxial cells in zebrafish. Prdm-1 acts as a transcriptional repressor in mediating the transcriptional repressor sox-6, which activates slow-twitch specific muscle gene expression. Zebrafish prdm-1 exhibits a dynamic and evolutionarily conserved expression pattern. Prdm-1 has been shown to be necessary for zebrafish forelimb development. The zebrafish narrowminded (nrd) mutation, which leads to absence of Rohon-Beard neurons and a reduction in neural crest cells and their derivatives, is a mutation in prdm-1.
Catalog #P5750-01V
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:5000-1:20,000
Western Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
Control Peptide P5750-01Y
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceZebrafish
ConcentrationNot determined
FormSupplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.05% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the intermediate region of zebrafish Prdm-1a.
SpecificityRecognizes zebrafish Prdm-1a.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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