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Abs to Transcription Factors, Zinc (Ring) Finger
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Anti -PRDM14 (PR Domain Zinc Finger Protein 14, PR Domain-containing Protein 14)
Anti -PRDM14 (PR Domain Zinc Finger Protein 14, PR Domain-containing Protein 14)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Sheep |
Affinity Purified |
E B IH |
|
| PRDM14 (PR [PRDI-BF1 and RIZ] domain containing protein 14) is a 64kD (predicted) member of the PR Domain family of proteins. It is expressed in embryonic stem cells and multiple tumor cell types. PRDM14 likely demonstrates histone methyltransferase activity, serving as a transcriptional repressor. It is suggested to block cell differentiation and maintain cell self-renewal, but also be necessary for germ cell lineage commitment. Human PRDM14 is 571aa in length. It contains one SET domain (aa253-371) followed by six C2H2 type Zn finger motifs (aa400-568). Over aa1-201, human PRDM14 shares only 46% aa identity with mouse PRDM14. | | | Catalog # | P5750-58 | | Applications | Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 0.5-1ug/ml | | Western Blot: 0.1ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Sheep | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with sterile PBS. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Purified, E. coli-derived, recombinant human PRDM14 (aa2-201; Accession #Q9GZV8). | | Specificity | Recognizes human PRDM14. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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