USBio Logo

P9005-74A Rat Anti-ProCollagen Type I, NT

Specifications
References
Clone Type
Monoclonal
Host
Rat
Source
Human
Swiss Prot
P02452
Isotype
IgG1
Clone Number
2Q576 (M-58)
Grade
Supernatant
Applications
IHC
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C

Collagen type I is present in soft connective tissue and bone where it represents approximately 90% of the organic matrix. Collagen type I is produced from procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. The propeptide levels can be measured in serum as indicators of collagen production. Elevated values of these propeptides in serum are found in patients with various bone metabolism defects. Procollagen type I C-terminal propeptide (PICP) has a molecular weight of approximately 100kD and the normal range in serum is 100-300ug/ml.

Applications
Suitable for use in Immunohistochemistry. Not recommended for Western Blot. Other applications have not been tested.
Recommended Dilutions
Immunohistochemistry (Fresh frozen tissue sections): 1:10,000-1:50,000 Immunohistochemistry (FFPE): 1:100-1:1000; Pretreatment with 1% trypsin, 20 minutes at RT. Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Human ProCollagen Type I.
Form
Supplied as a liquid.
Purity
Supernatant.
Specificity
Recognizes human ProCollagen Type I. Labels the amino-terminal pro-peptide. Localized intracellularly in cells producing Pro-collagen I. Does not stain mature collagen fibers in tissue.
References
1. Abdulghani, A.A., et al., Disease Management and Clinical Outcomes. 1(4): 136-141 (1998).
USBio References
No references available
Conjugates
Pricing
Order
Proceed to Checkout
Cart Summary
ProductSizeListYour PriceQtyExt Price
Subtotal:Subtotal:
Subtotal:Subtotal:
Total Coupon Savings:Total Coupon Savings:()
Your cart is currently empty.
- Coupon Code
Recently Viewed
Contact Us

Visit our technical library or contact our support staff to answer your questions.

Telephone:
1-800-520-3011

Library | Contact

Distributors

For customers outside of the United States, please use one of our many distributors.

View Distributors

Payment Methods

We accept the following payment methods as well as pay-by-invoice.

MasterCard Visa PayPal
© 2023-2024 United States Biological - All Rights Reserved